Quick Details
- ProName: Conotoxin G V (9CI)
- CasNo: 93438-65-4
- Molecular Formula: C88H138 N26 O44
- LimitNum: 0
Superiority
Conantokin G: inhibits NMDA receptors
Conantokin G has been isolated from the venom of the cone Conus geographus. This toxin selectively inhibits N…
Details
Conantokin G: inhibits NMDA receptors
Conantokin G has been isolated from the venom of the cone Conus geographus. This toxin selectively inhibits NR2B sub units of N-methyl-D-aspartate (NMDA) receptor-mediated calcium influx in central nervous system neurons. Conantokin G induces sleep-like symptoms in young mice and hyperactivity in older mice (SERT). This compound is currently being evaluated in phase II clinical trials under the name CGX-1007 by Cognetix Inc. It has been shown to be an effective antiepileptic agent in several animal models of seizures.
Purity rate: >98%
Price: 1mg - 190€